Pe file format on disk ex5a4d dos header coff header ox18000eeoo optional header section table code 8 data pe file format in memory dos header. Epsteinbarr virus ebv confers upon normal lymphocytes derived from bone marrow the ability to proliferate indefinitely in a test tube. Infections causing human cancer wiley online books. Generating lowoverhead dynamic binary translators mathias payer eth zurich, switzerland mathias. If you do not see its contents the file may be temporarily unavailable at the journal website or you do not have a pdf plugin installed and enabled in your browser. Activated potassium currents in rabbit ventricles with chronic myocardial infarction. One reason for this may be the incorporation of virus genes into the genes of host cells.
He has done research on cancer of the cervix, where he discovered the role of papilloma viruses, for which he received the nobel prize in physiology or medicine 2008. To explore attitudes to cervical cancer screening and sexual behaviour among human papillomavirus hpvvaccinated young women in southern sweden. Full text full text is available as a scanned copy of the original print version. Oncogenic viruses are able to induce or contribute to the development of specific cancers in animals and humans. Two teenage boys holding up a banner written in chinese at a pingpong tournament held at the chinese progressive associations headquarters. Conducting formative research for hpv vaccination program. Harald zur hausen, nobel prize laureate for physiology or medicine 2008, at a press conference at the karolinska in solna deutsch. September 1986 teil iv diplomatische falschungen 11 hannover 1988 hahnsehe buchhandlung. Links to pubmed are also available for selected references. Harald zur hausen simple english wikipedia, the free. Harald zur hausen born 11 mairch 1936 is a german virologist an professor emeritus. Menus ihr mittagessen auswahlten, dass vom cateringservice romer aus bitburg angeliefert wurde. Prevalence of antibodies to human papillomavirus type 8 in.
Garment workers marching in a protest with banners and signs. The international graduate school recognizes that doctoral students make an important contribution to the centers achievements and, we hope, encourages you to apply to. An interview with nobelist professor of virology harald zur hausen. His research made it possible to develop a vaccine against one of the most frequent cancer in women. Although, all cervical neoplasia comes always preceded of a hpv high risk infection, not all. Infections causing human cancer by zur hausen, harald ebook. Pdf cervical cancer is a sexually transmitted disease caused by the human papillomavirus hpv, especially hpv16 and 18. Harald zur hausen press conference dec 06th, 20084. Gutes zahlt alles, was mit diesem zur beforderung aufgegeben wird. Human papillomavirus has been detected in a variety of cutaneous premalignant and malignant conditions, as well as in benign cutaneous warts. From 1977 to 1987, harald zur hausen led a team of researchers across. Immortalization of human lymphocytes by epsteinbarr virus.
Professor zur hausen considers that the creation of an educational platform on paediatric virology is definitely very beneficial for young. What links here related changes upload file special pages permanent link page. Mathematiknaturwissenschaften universitat koblenzlandau vorgelegt am 15. This observation suggests that the parotid gland is, besides the peripheral lymphocytes, a site of lifelong persistence of epsteinbarr virus and probably the site of lowlevel virus production which may be the source of virus found in the oropharynx. He was enrolled in the university of bonn as a medical student in 1955, and continued medical studies in bonn, in hamburg, and dusseldorf. Harald zur hausen born 11 march 1936 in gelsenkirchen is a german virologist and professor emeritus. Professor harald zur hausen eas born at the 11th of march. Harald zur hausen, deutsches krebsforschungszentrum heidelberg, germany georgios papanicolaou. Dissociating neuronal gammaband activity from cranial and. Highlights in tumor virology heidelberg university. Gaststatte zur sonne familientradition seit 1884 inh. Inside the immortalized lymphocyte the ebv genome exists as a complete multicopy circular plasmid which is probably. Files are available under licenses specified on their description page.
Infections must be thought as one of the most important, if not the most important, risk factors for cancer development in humans. Harald zur hausen is awarded the nobel medicine prize. Lutz gissmann is known for his seminal research in the field of human papillomaviruses hpv and their causal association with human cancer, especially. For seroepidemiological studies, the hpv8 open reading frames for e1, e2, e4, e6, e7, and l1 were bacterially expressed as betagalactosidase fusion proteins, which were purified by preparative gel electrophoresis. Professor harald zur hausen, nobel laureate for 2008 in medicine or physiology for his work on human papillomavirus and carcinoma of the cervix, visited wits from 16 to 18 march 2011. Cervical cancer is identified as a sexually transmitted disease. Research profile harald zur hausen lindau mediatheque. Neoadjuvant chemotherapy nc is an established therapy in breast cancer, able to downstage positive axillary lymph nodes, but might hamper their detectibility. Harald zur hausen is a german virologist and professor emeritus. From 20002009, zur hausen was editorinchief of the international journal of cancer, and from 20062009 he was a member of the board of directors of the union for international cancer control uicc. He was introduced by professor bjorn vennstrom, member of the nobel committee for physiology or medicine. Gemeindezeitung ausgabe juli 2011 pdf 6,03 mb marktgemeinde gemeindezeitung nr. To evaluate the usefulness of this biomarker in the diagnosis of cases of cervical neoplasia we studied the immunohistochemical expression of p16ink4a in a large series of archival cervical biopsies arranged into tissue microarray format. At the end of the century, surgery is introduced for treating the disease.
Pdf on sep 28, 2015, claudia schlegel and others published lernen nach drehbuch find, read and cite all the research you need on researchgate. Persistence of epsteinbarr virus in the parotid gland. Alternatively, you can download the file locally and open with any standalone pdf reader. Zur hausen concluded that hpv, not hsv2, caused cervical cancer, which. Sixteen women aged 1726 years who had received the hpv vaccine were submitted to an individual semistructured interview. Neoadjuvant chemotherapy in breast cancer significantly. Leere notenblatter zur weiteren verwendung zum kostenlosen ausdrucken. Bill sugden studies the molecular biology of the human tumor virus, epsteinbarr virus ebv. Hausen s work focuses on the growth, division, and death of living cells and how they are regulated by their genes. The bamhi fragments of both clones were used to characterize the dna. Harald zur hausen was born on 11 march 1936 in gelsenkirchenbuer, the.
More than 70 years later, harald zur hausen demonstrated that human papillomavirus hpv can cause cervical cancer, for which he garnered. This page was last edited on 8 november 2018, at 15. Zur hausen studied medicine at the university of bonn and attended courses in biology. Zur hausen that earned him the nobel prize in the year 2008, it was determined that persistent infection with human papillomavirus hpv is the main causal agent for the development of cervical cancer. Two boys holding a banner drs northeastern university. Supplementary appendix this appendix has been provided by the authors to give readers additional information about their work. Zur hausen, former scientific director of the german cancer research center, a member of the helmholtz association, is recognized for finding that cervical cancer is caused by viral infections.
If these functions are out of balance, tumors can form. Garment workers protesting drs northeastern university. Available formats pdf please select a format to send. He was a research fellow at the university of dusseldorf and the childrens hospital of philadelphia, before being appointed assistant professor at the university of pennsylvania in 1968. In 1974 harald zur hausen postulated that a chronic infection with as yet unknown types of human papilloma virus, hpv, could give rise to cervical cancer. Epidemiologists discover that cervical cancer is common in female sex workers and also common in women whose husbands have a high number of sexual partners or were regular customers of. Deutsches krebsforschungszentrum, 69120 heidelberg, germany. Hier finden sie verschiedene notenblatter zum ausdrucken.
Even if clinical observations suggest lower lymph node yield lny after nc, data are inconclusive and it is unclear whether nc dependent parameters influence detection rates by axillary lymph node dissection alnd. Higher education development egnaton wg 5 universities. This process, called immortalization, is crucial to the pathogenesis of ebv infections. Hipp1,2andmarkus siegel1,2 1 centre for integrative neuroscience, university of tubingen,tubingen, germany 2 megcenter, university of tubingen, tubingen, germany edited by. Get a printable copy pdf file of the complete article 1020k, or click on a page image below to browse page by page. A new type of papillomavirus dna, its presence in genital cancer biopsies and in cell lines derived from cervical cancer pdf. Information from its description page there is shown below. Dissociating neuronal gammaband activity from cranial and ocular muscle activity in eeg joerg f. Harald zur hausen was born on march 11, 1936 in gelsenkirchenbuer, germany. To do these scans, the engine relies on a collection of all known virus definitions called a dat file in virusscan and a virus defi nition file in virex. This page was last edited on 16 august 2017, at 05. Network associates releases almost daily updates that are used by virusscan to detect the newest viruses on the windows platform. The epidermodysplasia verruciformisassociated human papillomavirus type 8 hpv8 poses a high risk for malignant conversion of skin lesions in patients with epidermodysplasia verruciformis. Attitude to cervical cancer screening and sexual behaviour.
Infections causing human cancer by harald zur hausen. Harald zur hausens experiments on human papillomavirus. Harald is the old norse form of the given name harold protogermanic harjawaldaz. All structured data from the file and property namespaces is available under the creative commons cc0 license. Bill sugden how epsteinbarr virus sustains its associated cancers dr. He haes duin resairch on cancer o the cervix, whaur he discovered the role o papilloma viruses, for which he received the nobel prize in pheesiology or medicine 2008. Tmas were constructed with tissue cores from archival formalin fixed, paraffinembedded donor tissues from 796 patients, and included cases of. Lutz gissmann born sept 18, 1949 in kaufbeuren, germany is a german virologist and was head of the division genome modifications and carcinogenesis at the german cancer research center dkfz in heidelberg until his retirement in 2015. Changes consistent with epidermis papillomavirus infection occurring in epidermal cysts have recently been reported in the dermatologic literature only in.
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